Bettina Weigelin is a Group Leader at the Department for Preclinical Imaging and Radiopharmacy at the University of Tübingen, Germany. She received her doctoral degree from Radboud University of Nijmegen, The Netherlands where she applied intravital multiphoton imaging to study cancer invasion mechanisms and immune function in solid tumors. She pioneered the application of third harmonic generation microscopy to map the structural microenvironment of solid tumors which lead to the discovery of protease-independent cancer cell invasion strategies along tissue guidance structures. In 2016 she received a Rubicon Young Investigator Award from the NWO to support her stay at MD Anderson Cancer Center, Houston, USA, where she used intravital microscopy to understand immunosuppression mediated by the bone microenvironment to develop novel strategies for immunotargeting of bone metastasis. Her group ‘Multiscale Immunoimaging’at the University of Tübingen combines advanced microscopic techniques with state-of-the art macroscopic imaging to gain mechanistic insight in kinetics and function of immune cells at the cellular and whole-body scale to improve cancer immunotherapies.